Radja Nainggolan will start from the bench on his return to the Inter squad as the Nerazzurri take on Empoli in their final match of 2018.
Luciano Spalletti makes three changes from the XI that started the Boxing Day win over Napoli, with Sime Vrsaljko, Matias Vecino and Keita Balde replacing Danilo D’Ambrosio, Marcelo Brozovic – who is suspended for this match – and Ivan Perisic.
Empoli make five changes from the side that lost to Torino on Wednesday, as Jacob Rasmussen, Joel Untersee, Afriyie Acquah, Manuel Pasqual and Antonino La Gumina all come into the team.
Empoli (3-5-2): Provedel; Veseli, Rasmussen, Silvestre; Untersee, Traore, Bennacer, Acquah, Pasqual; La Gumina, Caputo
Substitutes: Fulignati, Terracciano, Antonelli, Marcjanik, Capezzi, Zajc, Brighi, Ucan, Jakupovic, Mraz, Mchedlidze, Rodriguez
Unavailable: Krunic, Di Lorenzo, Polvani, Maietta
Inter (4-3-3): Samir Handanovic; Sime Vrsaljko, Stefan De Vrij, Milan Skriniar, Kwadwo Asamoah; Matias Vecino, Borja Valero, Joao Mario; Matteo Politano, Mauro Icardi, Keita Balde
Substitutes: Daniele Padelli, Tommaso Berni, Andrea Ranocchia, Danilo D’Ambrosio, Miranda, Dalbert, Roberto Gagliardini, Radja Nainggolan, Lautaro Martinez, Ivan Perisic, Antonio Candreva.
Unavailable: Marcelo Brozovic
Referee: Federico La Penna
Assistants: Vuoto, Marrazzo
Fourth Official: Di Martino
VAR Officials: Guida, Di Vuolo