Fatigue has become an issue for Inter Milan toward the end of an intense season, with a titanic clash against Barcelona waiting in the wings.

Per Gazzetta dello Sport via FCInterNews, there’s only one reasonable explanation for Inter’s fall from grace at the tail end of the campaign.

Simone Inzaghi had hoped to replicate Jose Mourinho’s success in 2010, yet his dream collapsed in epic fashion.

Indeed, AC Milan hammered the Nerazzurri in the return leg of their Coppa Italia semi-final tie.

Furthermore, Napoli leapfrogged Inter at Serie A’s table summit, opening up a three-point buffer.

Origins of Inter Milan Fatigue Concerns Ahead of Barcelona Clash

Inter Milan Francesco Acerbi
BOLOGNA, ITALY – APRIL 20: Francesco Acerbi of FC Internazionale looks on as he sits on the ground during the Serie A match between Bologna and FC Internazionale at Stadio Renato Dall’Ara on April 20, 2025 in Bologna, Italy. (Photo by Alessandro Sabattini/Getty Images)

Despite playing a game less than Barcelona, Inter players look far more tired than Hansi Flick’s charges.

Moreover, Lautaro Martinez is the only outfield Nerazzurri player to make the top-15 most-used Champions League list.

Therefore, the problem lies elsewhere. More precisely, it’s a high average age of Inter’s squad (29.3).

For comparison, Barcelona’s average is 24.9.

That is probably why Los Blaugranas look much fresher than their Serie A counterparts.

However, Flick’s side needed extra time to beat Real Madrid in the Copa del Rey final at the weekend.

It could be a factor on Wednesday.