Inter Milan head coach Cristian Chivu is likely to make drastic changes to his starting lineup for Friday’s home clash against Pisa.

According to Corriere dello Sport via FCInterNews, Ange-Yoan Bonny and Francesco Pio Esposito could lead the line tomorrow.

Marcus Thuram and Lautaro Martinez flopped in Tuesday’s 3-1 home defeat to Arsenal.

Therefore, they could be start on the bench when the Nerazzurri take on relegation-threatened Pisa in a must-win Serie A fixture.

Meanwhile, Pio Esposito and Bonny could spearhead Inter’s attack.

Inter Milan to Undergo Numerous Starting XI Changes vs Pisa

Francesco Pio Esposito Inter Milan
PISA, ITALY – NOVEMBER 30: Pio Esposito of FC Internazionale greets the fans after during the Serie A match between Pisa SC and FC Internazionale at Arena Garibaldi on November 30, 2025 in Pisa, Italy. (Photo by Gabriele Maltinti/Getty Images)

Stefan de Vrij and Yann Bisseck could return to the starting eleven, probably at the expense of Francesco Acerbi and Manuel Akanji, respectively.

Furthermore, Carlos Augusto might dislodge Federico Dimarco on the left wing, as the Italian star desperately needs some rest.

Meanwhile, one between Nicolo Barella and Piotr Zielinski could make way for Henrikh Mkhitaryan, with Petar Sucic expected to make another Serie A start.

Indeed, after scoring a delightful goal against Arsenal, the Croatian midfielder seems ready to start his second league match in 2026.