La Gazzetta dello Sport continues to propose a possible 4-4-2 for Inter against Sampdoria, with Melo being sure in the middle flanked by either Gnoukouri or Brozovic. And Biabiany and Perisic as wingers.
“In the first days of the week Mancini has tried the 4-4-2 insisting on playing Eder and Icardi close up top. Then he swerved to the 4-3-3 before Fiorentina. Yesterday afternoon at Appiano the coach went back to the 4-4-2 with Gnoukouri and Melo in inner midfield, with Eder and Icardi as strikers. Will training today make it official?”
Source: gazzetta.it

And the tactic is destroyed once Melo loses his temper and getting booked
Practice 4-4-2 and 4-3-3 all week.
Prediction: Starts with a 3-5-2.
I’m certain we will win if theres melo and gnoukouri in midfield. Melo can destroy, break up play, gnou can actually pass the ball and create movement. Perisic in this case will come into the game. If brozovic plays we will draw or lose, can’t have no brains in a 2 man mid with melo…
It is not about tactic, it is about mentality. If we will have winning mentality every tactic will be good. I really hope that against sampdoria mancini will finally inject positive and winning energy.. Look at valencia last several weeks, they came back from hell where Neville finally sort his team in good mood..